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:: Volume 8, Issue 1 (3-2022) ::
CJP 2022, 8(1): 648-654 Back to browse issues page
Pain intensity in Beta-thalassemia major patients and its related factors: A cross-sectional study in the south of Iran
Majid Naderi , Yasaman Khodabandeh , Ilia Mirzaei , Saeedeh Yaghoubi *
Assistant professor, Department of Pediatrics, Zahedan university of medical science, Zahedan, Iran , Yaghoubimd@yahoo.com
Abstract:   (743 Views)

Background and Objective: Beta-thalassemia is an autosomal recessive hemoglobinopathy that is thought to be the most common genetic mutation. Complications of iron overload and treatment processes are the most common cause of pain in these patients. Children with chronic diseases like thalassemia deal with a lot of pain during the diagnosis process, treatment and management of their disease. The aim of the present study was to evaluate pain in patients with thalassemia major.
Methods: The present descriptive-analytical study was performed on 211 patients with beta-thalassemia major, referred to Ali Asghar Clinic in Zahedan in 2017. A brief pain inventory (BPI) questionnaire was used to collect patients’ information analyzed using Chi-square t-test and Pearson correlation coefficient.
Findings: The mean pain intensity was 1.72±2.60 and 2.15±3.33 in patients ≤15 years and >15 years, respectively (p=0.011). The mean pain intensity was 2.37±1.49 and 3.52±2.33 in patients receiving oral and injectable iron chelators, respectively (p=0.004). However, no significant relationship was found between pain intensity with gender and presence of cardiomyopathy.
Conclusion: Since the mean pain intensity is associated with increasing age and type of iron depletion, it is recommended that at the beginning of diagnosis the necessary training on proper disease control and periodic examinations for timely diagnosis and treatment of complications of the disease.

Keywords: Brief Pain Inventory, Evaluation, Major Beta-Thalassemia, Pain
Type of Study: Research | Subject: Special
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Naderi M, Khodabandeh Y, Mirzaei I, Yaghoubi S. Pain intensity in Beta-thalassemia major patients and its related factors: A cross-sectional study in the south of Iran. CJP. 2022; 8 (1) :648-654
URL: http://caspianjp.ir/article-1-151-en.html

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Volume 8, Issue 1 (3-2022) Back to browse issues page
مجله کودکان کاسپین Caspian Journal of Pediatrics
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