Caspian Journal of Pediatrics

en Pain Intensity in Beta-Thalassemia Major Patients and Its Related Factors: A Cross-Sectional Study in the South of Iran تخصصي Special پژوهشي Research Background and Objective: Beta-thalassemia is an autosomal recessive hemoglobinopathy that is thought to be the most common genetic mutation. Complications of iron overload and treatment processes are the most common cause of pain in these patients. Children with chronic diseases like thalassemia deal with a lot of pain during the diagnostic process, treatment and management of their disease. The aim of the present study was to evaluate pain in patients with thalassemia major. Methods: The present descriptive-analytical study was performed on 211 patients with beta-thalassemia major, referred to Ali Asghar Clinic in Zahedan in 2017. A brief pain inventory (BPI) questionnaire was used to collect patients’ information analyzed using Chi-square t-test and Pearson correlation coefficient. Findings: The mean pain intensity was 1.72±2.60 score and 2.15±3.33 score in patients ≤15 years and >15 years, respectively (p=0.011). The mean pain intensity was 2.37±1.49 score and 3.52±2.33 score in patients receiving oral and injectable iron chelators, respectively (p=0.004). However, no significant relationship was found between pain intensity with gender and presence of cardiomyopathy. Conclusion: Since the mean pain intensity is associated with increasing age and the type of iron depletion, these factors should be considered as the main pain generator factors in these patients. Brief Pain Inventory, Evaluation, Major Beta-Thalassemia, Pain 648 654 http://caspianjp.ir/browse.php?a_code=A-10-189-2&slc_lang=en&sid=1 Majid Naderi dr.naderi@zaums.ac.ir 10031947532846004144 10031947532846004144 No Associate professor, Department of Pediatrics, Genetics of Non-Communicable Disease Research Center; Zahedan University of Medical Sciences, Zahedan, Iran. Yasaman Khodabandeh Y.khodabandeh@zaums.ac.ir 10031947532846004145 10031947532846004145 No Pediatrician, Zahedan University of Medical Science, Zahedan, Iran Ilia Mirzaei ilia.231197@gmail.com 10031947532846004146 10031947532846004146 No Medical school, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran Saeedeh Yaghoubi s.yaghoubi@zaums.ac.ir 10031947532846004147 10031947532846004147 Yes Assistant professor, Department of Pediatrics, Zahedan university of medical science, Zahedan, Iran