دوره 9، شماره 1 - ( 12-1401 )
جلد 9 شماره 1 : e12 |
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Kalenahalli J, Hassan Vasudev P, Vadambal Gopalakrishna M, Huchhavanahalli Rudrappa N. Severe Bradycardia caused by Octreotide in an Adolescent: A Case Report. CJP 2023; 9 (1) :12-12
URL: http://caspianjp.ir/article-1-209-fa.html
URL: http://caspianjp.ir/article-1-209-fa.html
Severe Bradycardia caused by Octreotide in an Adolescent: A Case Report. مجله کاسپین کودکان. 1401; 9 (1) :12-12
چکیده: (1741 مشاهده)
Background and Objective: Octreotide is a somatostatin analogue used to control upper gastrointestinal (GI) bleeding. Adverse effects observed include hyperglycemia, growth hormone deficiency, hypertension, Q-T interval prolongation, and ventricular fibrillation. In rare cases, mild bradycardia has been reported.
Case Report: A 16-year-old boy was admitted with shock due to hematemesis and melena a bleeding duodenal ulcer. He was treated with an intravenous venous octreotide infusion at a dose of 1 microgram/kg/hour, and bleeding was controlled with coagulation forceps and adrenaline injection. Because of rebleeding, octreotide was increased to 2 micrograms/kg/hour because of bleeding again. After 24 hours, he developed severe bradycardia (pulse rate (PR) 45/minute). His PR increased to 66/minute by 12 hours after octreotide was discontinued.
Conclusion: Octreotide can cause significant cardiovascular side effects. Bradycardia and cardiac conduction blocks may affect the hemodynamics of a child with acute GI bleeding.
Case Report: A 16-year-old boy was admitted with shock due to hematemesis and melena a bleeding duodenal ulcer. He was treated with an intravenous venous octreotide infusion at a dose of 1 microgram/kg/hour, and bleeding was controlled with coagulation forceps and adrenaline injection. Because of rebleeding, octreotide was increased to 2 micrograms/kg/hour because of bleeding again. After 24 hours, he developed severe bradycardia (pulse rate (PR) 45/minute). His PR increased to 66/minute by 12 hours after octreotide was discontinued.
Conclusion: Octreotide can cause significant cardiovascular side effects. Bradycardia and cardiac conduction blocks may affect the hemodynamics of a child with acute GI bleeding.
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