en عمومى General گزارش مورد case report <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:times new roman;"><span style="color:#008080;"><strong><em>Background:</em></strong></span> &ldquo;Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections&rdquo;, or PANDAS, is a syndrome characterized by acute-onset obsessive-compulsive disorder (OCD) and/or tics accompanied by the neuropsychiatric symptoms. This case is reported because of its rarity.<br> <span style="color:#008080;"><strong><em>Case report:</em></strong></span> A 6.5-year-old boy with swollen tonsils, high-grade fever and rash was admitted to Amirkola Children&rsquo;s Hospital, Northern Iran. Thereafter he got involved with tachycardia, hypotension, suppurative conjunctivitis and swelling of extensor surfaces of extremities. In addition, after the onset of fever, he had some neuropsychiatric problems such as social isolation, irritability, aggression, oppositional behavior, behavioral regress, unusual sound production, repeated vilifications, loss of appetite and handwriting deterioration. He was treated with intravenous immunoglobulin (IVIG). The patient was discharged from the hospital in a good condition.<br> <span style="color:#008080;"><strong><em>Conclusions:</em></strong></span> The medical treatment of underlying disease leads to remarkable patient&#39;s neuropsychological and OCD symptoms. PANDAS should be diagnosed in the streptococcal infections associated with abrupt behavioral symptoms and treated with IVIG and antibiotics<span dir="RTL">.</span></span></span></div> Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections, Pediatric, Autoimmune diseases, IVIG 325 328 http://caspianjp.ir/browse.php?a_code=A-10-121-1&slc_lang=en&sid=1 Mohsen Mohammadi Dr.mohamadi61@yahoo.com 10031947532846004951 10031947532846004951 No Non-communicable pediatric diseases research center, Babol university of medical sciences, Babol, IR Iran Ehsan Abiri Dr.abiry@yahoo.com 10031947532846004952 10031947532846004952 Yes Non-communicable pediatric diseases research center, Babol university of medical sciences, Babol, IR Iran Mahmoud Khodabandeh khodabandeh@farabi.tums.ac.ir 10031947532846004953 10031947532846004953 No Division of infectious diseases, children’s medical center, pediatrics’ center of excellence, Tehran university of medical sciences, Tehran, Iran Armon Massoodi armonmassoodi@gmail.com 10031947532846004954 10031947532846004954 No Assistant Professor of child and adolescent Psychiatry, Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR Iran