en تخصصي Special پژوهشي Research <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:times new roman;"><span style="color:#008080;"><strong><em>Background:</em></strong></span> The methods of baby&#39;s position are an important critical factor in ventilation and oxygenation of tissues. Although the prone position as one of the recommended position has beneficial effect on the development of premature infants, little research has been done.<br> <span style="color:#008080;"><strong><em>Methods:</em></strong></span> In a clinical trial among mechanically ventilated infants, hospitalized in the neonatal intensive care units (NICUs), 35 preterm infants were selected in 2014-2015. Each infant was positioned in a supine (control group) and prone (case group) positions for 2 hours, respectively. The values of blood oxygen saturations (SpO₂) and heart rates were assessed and recorded every 10 minutes by a cardio-respiratory monitoring device. Data analysis was performed using SPSS v.22.<br> <span style="color:#008080;"><strong><em>Results:</em></strong></span> The mean heart rates were 136.909&plusmn;2.861 and 136.600&plusmn;2.560 beats per minute in the supine and prone positions, respectively. Heart rates were within the normal ranges in both positions, but the range of fluctuation was slightly lower and statistically non-significant in the prone position (p-value=0.805). The average of SpO₂ was 92.364% and 95.046% in the supine and prone positions, both of them were within the normal range.<br> <span style="color:#008080;"><strong><em>Conclusions:</em></strong></span> This study showed that the prone position compared to the supine position has a more favorable effect of SpO₂ and heart rate fluctuations in preterm infants.</span></span></div> Blood Oxygen Saturations, Heart Rate, Position, Premature Infant, Ventilator 298 302 http://caspianjp.ir/browse.php?a_code=A-10-47-2&slc_lang=en&sid=1 Tahereh Babuyeh rohanresearch88@gmail.com 10031947532846002667 10031947532846002667 No Student Committee Research, Babol University of Medical Sciences, Babol, Iran Roya Farhadi CRDU.Rohan@mubabol.ac.ir 10031947532846002668 10031947532846002668 No Assistant Professor of Neonatal Specialty, Mazandaran University of Medical Sciences, Sari, Iran. Yadollah Zahed Pasha yzpasha@yahoo.com 10031947532846002669 10031947532846002669 No Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. Mohsen Haghshenas Mojaveri matia.mojaveri@yahoo.com 10031947532846002670 10031947532846002670 Yes Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. - The Clinical Research Development unit of Rouhani Hospital, Babol University of Medical Sciences, Iran