en عمومى General پژوهشي Research <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14.0pt"><b><span style="color:#24a3a0">Background and Objective:</span></b> The SARS-CoV-2 virus has affected people of all ages. Children with SARS-CoV-2 infections are not a widely explored area, but they are important in prognosticating COVID-19 infections. The aim of this study was to investigate the clinical epidemiological traits of SARS-CoV-2-affected children and their correlation with comorbidities.</span><br> <span style="line-height:14.0pt"><b><span style="color:#24a3a0">Methods:</span></b> A single-centre retrospective study was done among 81 COVID-19-confirmed children from April to August 2023 in Mysuru, India. Data on epidemiological characteristics, outcome status, and systemic co-infections was analyzed using IBM SPSS 26. The relationship between categorical variables was established using the chi-square test/Fisher&rsquo;s exact test. The level of statistical significance was set at a p-value < 0.05.</span><br> <span style="line-height:14.0pt"><b><span style="color:#24a3a0">Findings:</span></b> The maximum COVID-19-positive children belonged to the age group of 0-2 (34.6%). Neurological co-infections were the most prevalent at 47.6%, presenting with axial hypotonia, febrile seizures, hypoglycemia, and cerebral encephalopathy. Neurological co-infections were the most prevalent at 47.6%, presenting with axial hypotonia, febrile seizures, hypoglycemia, and cerebral encephalopathy. There was a significant association between outcome status and cardiovascular system involvement (P value = 0.003).</span><br> <span style="line-height:14.0pt"><b><span style="color:#24a3a0">Conclusion:</span></b> <span style="color:#000000;">Since </span>most of the children had a co-infections and the most common cause was bactrial infection, children should be monitored for at least one month after hospitalization. The goal is early detection to stop co-infections or empirical treatment in high-risk cases.</span></span></span></div> Child, Co-Infection, COVID-19, Pandemic 0 0 http://caspianjp.ir/browse.php?a_code=A-10-319-1&slc_lang=en&sid=1 Prajwala Hassan Vasudev prajwalahv@gmail.com 10031947532846005056 10031947532846005056 No JSS Medical College, JSS Academy of Higher Education and Research, India Ritik Raj raj345824@gmail.com 10031947532846005057 0009-0008-2664-3190 No JSS Medical College, JSS Academy of Higher Education and Research, India Deepak Anil deepakanil7@gmail.com 10031947532846005058 10031947532846005058 Yes JSS Medical College, JSS Academy of Higher Education and Research, India