en عمومى General پژوهشي Research <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:15.0pt"><b><span style="color:#24a3a0">Background and Objective:</span></b> Acute exacerbation of bronchial asthma is a very common presentation in the pediatric emergency department, thus being a major cause of morbidity in children. Intravenous magnesium sulfate is often used for the management of acute asthma. The actual association of serum magnesium levels with the severity of the disease has been explored in various studies but lacks concrete results, especially in Indian children. The aim of this study was to assess serum magnesium levels in children with acute bronchial asthma and determine the association between magnesium levels and various parameters in asthma.</span><br> <span style="line-height:15.0pt"><b><span style="color:#24a3a0"><span style="letter-spacing:.2pt">Methods:</span></span></b><span style="letter-spacing:.2pt"> This cross-sectional study was conducted in a tertiary care center in New Delhi in the year 2021-22. A total of 40 children aged 6-11 years presenting to the emergency department with acute exacerbation were included. Serum magnesium levels were determined in all patients who came to the emergency department with an acute exacerbation of bronchial asthma. The prevalence and association between hypomagnesemia and various disease and population variables were determined.</span></span><br> <span style="line-height:15.0pt"><b><span style="color:#24a3a0">Findings:</span></b> The prevalence of hypomagnesemia was 20% in the included patients. Lower magnesium levels were found to be associated with lower oxygen saturation on admission, longer duration of hospitalization, deranged pulmonary function tests, and the need for mechanical ventilation.</span><br> <span style="line-height:15.0pt"><b><span style="color:#24a3a0">Conclusion:</span></b> The results showed that hypomagnesemia was significantly associated with increased severity of bronchial asthma.</span></span></span></div> Asthma, Child, Hypomagnesemia, Hypoxia 0 0 http://caspianjp.ir/browse.php?a_code=A-10-299-1&slc_lang=en&sid=1 Samridhi Chowdhary dr.samridhichowdhary@gmail.com 10031947532846004746 0009-0004-3309-7635 No Maulana Azad Medical College, New Delhi, India Rajeshwari Krishnan rajeshwari.dr@gmail.com 10031947532846004747 10031947532846004747 No Maulana Azad Medical College, New Delhi, India Deepak Kumar deepakk70@gmail.com 10031947532846004748 10031947532846004748 Yes Maulana Azad Medical College, New Delhi, India Binita Goswami binita.dr@gmail.com 10031947532846004749 10031947532846004749 No Maulana Azad Medical College, New Delhi, India