en تخصصي Special پژوهشي Research <p class="MsoNormal" style="line-height: 14pt direction: ltr unicode-bidi: embed"><span style="font-family:times new roman;"><span style="color:#008080;"><b><i>Background</i></b><b><i>:</i></b></span><span style="font-size: 10pt"><span style="color:#008080;"> </span>Due to difficulty of obtaining a 24h urine (especially in children), a random urine calcium sample is recommended to detect of hypercalciuria. However, recent studies have shown that the urinary calcium/creatinine ratio varies with age and geographic areas. So, the aim of this study was determining the normal value of urinary calcium to creatinine ratio in healthy adolescent&rsquo;s children.</span></span></p> <p class="MsoNormal" style="line-height: 14pt direction: ltr unicode-bidi: embed"><span style="font-family:times new roman;"><span style="color:#008080;"><b><i>Methods:</i></b><span style="font-size: 10pt">&nbsp;</span></span><span style="font-size: 10pt">Four hundred eight children of 12 to 14-year-old were randomly selected from middle school in Babol (north of Iran) and early morning urinary samples of them were studied for determining normal urine Ca/Cr, Na/Cr and K/Cr ratios. Children who had the family with the history of renal disease were excluded from this study.</span></span></p> <p class="MsoNormal" style="line-height: 14pt direction: ltr unicode-bidi: embed"><span style="font-family:times new roman;"><span style="color:#008080;"><b><i>Results:</i></b></span><span style="font-size: 10pt"> In this study the 50% and 95% of urinary Ca/Cr ratio were 0.08</span><span style="font-size: 10pt">&plusmn;0.02 and 0.13 mg/mg for the whole group. The mean of urinary Ca/Cr ratio in boys and girls were 0.08&plusmn;0.03 and 0.08&plusmn;0.02, respectively. The mean of urinary Na/Cr ratio in boys was 1.4&plusmn;0.48 and in girls was 1.21&plusmn;0.33. Also, the mean of urinary K/Cr ratio in boys and girls were 0.30&plusmn;0.11 and 0.29&plusmn;0.10, respectively.</span></span></p> <p class="MsoNormal" style="line-height: 14pt direction: ltr unicode-bidi: embed"><span style="font-family:times new roman;"><span style="color:#008080;"><b><i>Conclusions:</i></b></span><span style="font-size: 10pt"> This study was shown that the urinary Ca/Cr ratio of these children is different from other geographic areas. Also, a direct relationship was seen between urinary Ca/Cr ratio, Na/Cr and k/Cr ratios.</span></span></p> Adolescents, Normal Urinary Calcium Creatinine Ratio, Normal Urinary Sodium Creatinine Ratio, Normal Urinary Potassium Creatinine Ratio 9 12 http://caspianjp.ir/browse.php?a_code=A-10-26-1&slc_lang=en&sid=1 Hadi Sorkhi hadisorkhi@yahoo.com 10031947532846001191 10031947532846001191 Yes Non-Communicable Pediatric Diseases Research Center Mahmood Hajiahmadi 10031947532846001192 10031947532846001192 No Department of Social Medicines and Health Mehdi Pouramir 10031947532846001193 10031947532846001193 No Cellular and Molecular Biology Research Center, Health Research Institute Mohsen Akhavan 10031947532846001194 10031947532846001194 No Pediatrics Medicine Research Center Malihe Chooghadi 10031947532846001195 10031947532846001195 No Non-Communicable Pediatric Diseases Research Center, Babol University of Medical Sciences, Babol, IR Iran. Sahar Sadr Moharrerpour 10031947532846001196 10031947532846001196 No Non-Communicable Pediatric Diseases Research Center