en عمومى General گزارش مورد case report <div style="text-align: justify;"><span style="font-family:Times New Roman;"><span style="font-size:14px;"><span style="line-height:14.0pt"><span sans-serif=""><b><span new="" roman="" times=""><span style="color:#24a3a0">Background and Objective:</span></span></b> <span lang="EN-IN" new="" roman="" times="">Octreotide is a somatostatin analogue used to control upper gastrointestinal (GI) bleeding. Adverse effects observed include hyperglycemia, growth hormone deficiency, hypertension, Q-T interval prolongation, and ventricular fibrillation. In rare cases, mild bradycardia has been reported</span><span new="" roman="" times="">.</span></span></span><br> <span style="line-height:14.0pt"><span sans-serif=""><b><span new="" roman="" times=""><span style="color:#24a3a0"><span style="letter-spacing:.2pt">Case Report:</span></span></span></b> <span lang="EN-IN" new="" roman="" times=""><span style="letter-spacing:.2pt">A 16-year-old boy was admitted with shock due to hematemesis and melena a bleeding </span></span><span new="" roman="" times=""><span style="letter-spacing:.2pt">duodenal ulcer</span></span><span lang="EN-IN" new="" roman="" times=""><span style="letter-spacing:.2pt">. He was treated with an intravenous venous octreotide infusion at a dose of 1 microgram/kg/hour, and bleeding was controlled with coagulation forceps and adrenaline injection. </span></span><span new="" roman="" times=""><span style="letter-spacing:.2pt">Because of rebleeding, octreotide was</span></span><span lang="EN-IN" new="" roman="" times=""><span style="letter-spacing:.2pt"> increased to 2 micrograms/kg/hour because of bleeding again. After 24 hours, he developed severe bradycardia (pulse rate (PR) 45/minute). His PR increased to 66/minute by 12 hours after </span></span><span new="" roman="" times=""><span style="letter-spacing:.2pt">octreotide was discontinued.</span></span></span></span><br> <b><span style="line-height:107%"><span new="" roman="" times=""><span style="color:#24a3a0">Conclusion:</span></span></span></b> <span lang="EN-IN"><span style="line-height:107%"><span new="" roman="" times="">Octreotide can cause significant cardiovascular side effects. Bradycardia and cardiac conduction blocks may affect the hemodynamics of a child with acute GI bleeding</span></span></span><span style="line-height:107%"><span new="" roman="" times="">.</span></span></span></span></div> Bleeding, Child, Infusion, Octreotide, Severe Bradycardia 12 12 http://caspianjp.ir/browse.php?a_code=A-10-265-1&slc_lang=en&sid=1 Jagadishkumar Kalenahalli kjagadishkumar@jssuni.edu.in 10031947532846004692 10031947532846004692 Yes MBBS., MD; Professor of Pediatrics, Jss Medical College, Jss Academy of Higher Education and Research, Mysore, India Prajwala Hassan Vasudev Prajwalahv@jssuni.edu.in 10031947532846004693 10031947532846004693 No MBBS, MD; Assistant Professor of Pediatrics., Jss Medical College, Jss Academy of Higher Education and Research, Mysore, India Manjunath Vadambal Gopalakrishna vgmanjunath@jssuni.edu.in 10031947532846004694 10031947532846004694 No MBBS.DCH., DNB.; Professor of Pediatrics, Jss Medical College, Jss Academy of Higher Education and Research, Mysore, India Nandish Huchhavanahalli Rudrappa nandishhr@jssuni.edu.in 10031947532846004695 10031947532846004695 No Senior Resident in Pediatrics, Jss Medical College, Jss Academy of Higher Education and Research, Mysore, India