Caspian Journal of Pediatrics

en Relationship between Serum Sodium Level and Severity of Bronchiolitis in Children Hospitalized in Amirkola Children's Hospital, Iran تخصصي Special كاربردي Applicable <div style="text-align: justify;">Background and Objective: Despite the self-limiting nature of bronchiolitis, its severe forms require hospitalization. Electrolyte imbalance during bronchiolitis is common, however, the relationship between bronchiolitis severity and serum sodium (Na) levels has not been well studied. The purpose of this study was to investigate the relationship between serum Na level and bronchiolitis severity. Methods: This cross-sectional study included hospitalized children with bronchiolitis at Amirkola Children’s Hospital, Babol, Iran, from May 2020 to May 2021. Diarrhea, underlying disease, glucocorticoid intake, and intravenous fluid therapy before admission were considered exclusion criteria. The Bierman-Pierson scale was used to evaluate the severity of the disease, and hyponatremia was divided into mild, moderate, and severe groups. Variables were analyzed using Statistical Packages for Social Sciences (SPSS) 26. A value of P<0.05 was considered significant. Findings: Sixty-one children (55.7% male) with a mean age of 5.19 ± 4.36 months were enrolled in the study, with most (50.8%) belonging to the mild form of the disease. The mean serum Na levels based on the severity of bronchiolitis were 136.22 (SD: 2.99), 133.76 (SD: 3.88), and 130.50 (SD: 11.45) in the mild, moderate, and severe groups, respectively. There was a statistically significant relationship between serum sodium level and severity of bronchiolitis (P-value = 0.013). Conclusion: The results showed that higher severity of bronchiolitis was associated with an increased risk of hyponatremia. Therefore, periodic monitoring and correction of hyponatremia in children with bronchiolitis, especially at younger ages, is necessary to improve the outcome of the disease.</div> Bronchiolitis, Child, Electrolyte imbalance, Prognosis, Sodium 6 6 http://caspianjp.ir/browse.php?a_code=A-10-117-4&slc_lang=en&sid=1 Shiva Khanbabaie shivakhanbabaee@gmail.com 10031947532846004637 10031947532846004637 No Student Research Committee, Babol University of Medical Sciences, Babol, Iran Masoud Kiani m.kiani@mubabol.ac.ir 10031947532846004638 10031947532846004638 Yes Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Iraj Mohammadzadeh i.mohammadzadeh@mubabol.ac.ir 10031947532846004639 10031947532846004639 No The Clinical Research Development Unit of Amirkola Children's Hospital, Babol University of Medical Sciences, Babol, IR Iran Hadi Sorkhi h.sorkhi@mubabol.ac.ir 10031947532846004640 10031947532846004640 No Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR Iran Mahmoud Hajiahmadi hajiahmadi@yahoo.com 10031947532846004641 10031947532846004641 No Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR Iran Kiarash Saleki kiarash_saleki@icloud.com 10031947532846004642 10031947532846004642 No Student Research Committee, Babol University of Medical Sciences, Babol, Iran