Volume 8, Issue 2 (9-2022)                   CJP 2022, 8(2): 0 | Back to browse issues page


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Srivastava T, Mehra N, Rathaur V K, Ahmad N. Correlation between Serum Alkaline Phosphatase and Vitamin D3 Levels among 1-14 Years Old Malnourished Children: A Descriptive Observational Study. CJP 2022; 8 (2) :711-716
URL: http://caspianjp.ir/article-1-177-en.html
Assistant Professor, Department of Pediatrics, Alfalah Medical College, India , nikhilpaediatrics@gmail.com
Abstract:   (1887 Views)
Background and Objective: Vitamin D deficiencies are highly prevalent globally, but the correlation between serum alkaline phosphatase and vitamin D3 deficiency among Indian children is seldom investigated. To describe the correlation between vitamin D3 levels and serum alkaline phosphatase levels among children admitted to malnutrition in the pediatric wards in the tertiary care center.
Methods: This descriptive observational study was conducted among 250 malnourished children aged between 1–14-years, attending the outpatient department of a rural tertiary care center in Faridabad, Haryana. The study was conducted from February 2019 to March 2020. A detailed history was taken using a questionnaire administered to the parents/guardians of the enrolled children. Demographic data, serum alkaline phosphatase, and vitamin D3 levels were used for analysis. The collected data were transferred and analyzed in coGuide software.
Findings: The mean age of children was 6.32 ± 4.15 years (range 1-14 years). More than half (64.50%) of all malnourished children were males. Mean serum alkaline phosphatase levels were 226.95 ± 169.39 u/l (range 89 - 2341), and the mean serum vitamin D3 levels were 19.79±11.99 ng/ml (range 5.49 to 69.53 ng/ml). A weak negative correlation between serum alkaline phosphate (U/L) and serum vitamin D3 (ng/ml) (rs: -0.105, P: 0.118) was observed.
Conclusion: There is a negative correlation between serum alkaline phosphate and serum vitamin D3. As vitamin D3 levels are low in malnourished children, active surveillance and aggressive management are the need of the hour.
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Type of Study: Research | Subject: General

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